<ruby id="wjn4g"></ruby>
<source id="wjn4g"></source>
<i id="wjn4g"></i>
<output id="wjn4g"></output>
<u id="wjn4g"></u>
</noscript> <script> function stop(){ return false; } document.oncontextmenu=stop; </script> <div class="view-html"> <div class="container-fluid clearfix column navbar navbar-default layout_152551"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> <span class="sr-only">網站名稱</span><span class="icon-bar"></span><span class="icon-bar"></span><span class="icon-bar"></span> </button> <div class="container"> <div id="navbar" class="navbar-collapse collapse"> <ul class="nav navbar-nav"> <li class="oen"><a href="/">網站首頁</a></li> <li class="oen dropdown"> <a href="/index.php?case=archive&act=list&catid=21" class="toogle" >產品列表<span class="caret"></span></a> <ul class="two dropdown-menu"> <li> <a title="動物外泌體" href="/index.php?case=archive&act=list&catid=22" >動物外泌體</a> </li> <li> <a title="植物外泌體" href="/index.php?case=archive&act=list&catid=23" >植物外泌體</a> </li> <li> <a title="微生物外泌體" href="/index.php?case=archive&act=list&catid=24" >微生物外泌體</a> </li> </ul> </li> <li class="oen dropdown"> <a href="/index.php?case=archive&act=list&catid=3" class="toogle" >服務項目<span class="caret"></span></a> <ul class="two dropdown-menu"> <li> <a title="超速離心" href="/index.php?case=archive&act=list&catid=15" >超速離心</a> </li> <li> <a title="電鏡拍攝" href="/index.php?case=archive&act=list&catid=16" >電鏡拍攝</a> </li> <li> <a title="粒徑分析" href="/index.php?case=archive&act=list&catid=17" >粒徑分析</a> </li> <li> <a title="蛋白檢測" href="/index.php?case=archive&act=list&catid=18" >蛋白檢測</a> </li> </ul> </li> <li class="oen dropdown"> <a href="/index.php?case=archive&act=list&catid=2" class="toogle" >研究前沿<span class="caret"></span></a> <ul class="two dropdown-menu"> <li> <a title="行業資訊" href="/index.php?case=archive&act=list&catid=13" >行業資訊</a> </li> <li> <a title="技術方法" href="/index.php?case=archive&act=list&catid=10" >技術方法</a> </li> <li> <a title="文獻資料" href="/index.php?case=archive&act=list&catid=6" >文獻資料</a> </li> <li> <a title="數據共享" href="/index.php?case=archive&act=list&catid=8" >數據共享</a> </li> </ul> </li> <li class="oen dropdown"> <a href="/index.php?case=archive&act=list&catid=1" class="toogle" >關于我們<span class="caret"></span></a> <ul class="two dropdown-menu"> <li> <a title="平臺介紹" href="/index.php?case=archive&act=list&catid=4" >平臺介紹</a> </li> <li> <a title="團隊成員" href="/index.php?case=archive&act=list&catid=11" >團隊成員</a> </li> <li> <a title="發展歷程" href="/index.php?case=archive&act=list&catid=12" >發展歷程</a> </li> <li> <a title="送樣須知" href="/index.php?case=archive&act=list&catid=19" >送樣須知</a> </li> <li> <a title="常見問題" href="/index.php?case=archive&act=list&catid=20" >常見問題</a> </li> </ul> </li> <li class="oen"> <a href="/index.php?case=archive&act=list&catid=5" >聯系我們</a> </li> <li class="oen active"> <a href="/index.php?case=archive&act=list&catid=14" >案例展示</a> </li> </ul> </div><div class="row layout_315462" style="float: left;"> <a href="" class="navbar-brand text-center"><img src="/html/upload/images/201904/15563778334246.jpg" class="img-responsive" alt="廈門恩賽爾生物科技有限公司（外泌體標準化服務平臺）"></a> </div> </div> <div class="top-nav-right navbar-right layout_602435"> <ul> <li id="fat-menu" class="dropdown"> <a class="dropdown-toggleglyphicon glyphicon glyphicon-globe" data-toggle="dropdown" role="button" aria-expanded="false"></a> <ul class="dropdown-menu" aria-labelledby="drop3"> <li> <a id="StranLink" name="StranLink">繁體</a> </li> <li> <a target="_blank">公司網站</a> </li> </ul> </li> <li class="glyphicon glyphicon-search" data-toggle="modal" data-target=".bs-example-modal-lg-search" aria-hidden="true"> </li> </ul> </div> </div> </div> <div class="view-html"> <div class="container-fluid clearfix layout_262063"> <div class="column"> <div class="column visual-slide"> <!-- Bootstrap bootstrap-touch-cslider Slider Main Style Sheet --> <div id="bootstrap-touch-cslider" class="carousel bs-slider fade row control-round indicators-line" data-ride="carousel" data-pause="hover" data-interval="5000"> <!-- Indicators --> <ol class="carousel-indicators"> <li data-target="#bootstrap-touch-cslider" data-slide-to="0" class="active"></li> </ol> <!-- Wrapper For Slides --> <div class="carousel-inner" role="listbox"> <!-- Second Slide --> <div class="item active"> <!-- Slide Background --> <img src="/html/upload/images/201904/15564153413583.png" alt="" class="slide-image"> </div> <!-- End of Slide --> </div><!-- End of Wrapper For Slides --> </div></div> </div> </div> <div class="container-fluid clearfix layout_67908" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_863630"> <div class="column"> <div class="column visual-category-notifications"> <nav class="sub_menu"> <ol class="breadcrumb"> <span class="glyphicon glyphicon-list"></span> <li><a href="/">網站首頁</a></li> <li><a title="案例展示" href="/index.php?case=archive&act=list&catid=14">案例展示</a></li> </ol> </nav> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_564394 text-center text-bold" style="font-size: 20px; color: rgb(0, 0, 0); margin-top: 30px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_439253"> <div class="column"> <div class="column visual-conent-title"> <p class="content-title"> 外泌體LncRNA促進腫瘤細胞耐藥性</p> <div class="clearfix"> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_610181" style="margin-top: 0px;"> <div class="column"> <div class="container clearfix layout_148235 text-center text-bold" style="font-size: 20px; color: rgb(0, 0, 0);"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_369638 text-center" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_13448"> <div class="column"> <div class="col-md-12 layout_455380"> <div class="col-md-2 column"> </div> <div class="col-md-8 column"> <div class="column visual-conent-author visual-inline-block"> <p class="content-author"> <span>作者：</span>admin</p> </div> <div class="column visual-conent-adddate visual-inline-block" style="padding-left: 15px; padding-right: 15px;"> <p class="content-adddate"> <span>添加時間：</span>2019-04-20 13:10:20</p> </div> <div class="column visual-conent-source visual-inline-block"> <p class="content-source"> <span>來源：</span>云序生物</p> </div> <div class="column visual-category-statistics visual-inline-block" style="padding-left: 15px;"> 瀏覽：<script src="/index.php?case=archive&act=view_js&aid=33"></script></div> </div> <div class="col-md-2 column"> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_617573" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_903271"> <div class="column"> <div class="column visual-category-title"> <div class="content_tools_box"> <p class="content_tools"> <a href="javascript:CallPrint('print');">打印本文</a> <a href="javascript:doZoom(14)">小</a> <a href="javascript:doZoom(18)">中</a> <a href="javascript:doZoom(20)">大</a> </p> <div class="clearfix"> </div> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_43304" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_784828"> <div class="column"> <div class="column visual-conent"> <p><strong>題目</strong>：Exosome-Transmitted lncARSR Promotes Sunitinib Resistance in Renal Cancer by Acting as a Competing Endogenous RNA</p><p><strong>期刊</strong>：Cancer Cell</p><p><strong>影響因子</strong>：27.41</p><p><strong>簡介</strong>：本文闡述了疾病相關LncRNA參與腎癌耐藥性及通過外泌體傳播的生理機制。首先，作者通過高通量手段檢測了野生型細胞和耐藥型細胞中差異表達的LncRNA，并通過病人源性異種移植模型(PDX)鑒定到8條疑似致病LncRNA。將其中一條LncRNA-LncARSR (Activated in RCC with Sunitinib Resistance)敲除后，細胞耐藥性顯著增強。進一步研究表明LncARSR與腎癌細胞增殖、粘附等表型密切相關。作者研究發現，LncARSR主要存在于細胞外泌體中，并且耐藥細胞外泌體LncRNA含量要遠高于野生型細胞。作者隨后通過RNA Pull Down實驗證實核不均一性核糖核蛋白A2B1(hnRNPA2B1)負責包埋LncARSR進入外泌體。當提取耐藥細胞外泌體孵育到野生型細胞后，野生型細胞胞內LncARSR含量增加，細胞耐藥性增強。而胞內LncARSR主要發揮miRNA海綿功能，通過競爭性結合miRNA-34和miRNA-449，促進AXL和c-MET表達及下游STAT3、AKT、ERK信號通路的活化，最終導致舒尼替尼耐藥性形成。</p><p style="text-align: center;"><img src="/html/upload/images/201904/15563523937502.png" width="960" height="394"/></p></div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_676599" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_158624"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_667472"> <div class="column"> <div class="container clearfix layout_381979"> <div class="column"> <div class=" visual-conent-form"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_886423" style="margin-top: 15px; margin-bottom: 5px;"> <div class="column"> <div class="container clearfix layout_390441"> <div class="column"> <div class="column visual-conent-page"> <div id="page"> <strong>上一篇</strong><a href="/index.php?case=archive&act=show&aid=32">大腦創傷外泌體中環狀RNA變化的研究</a> <div class="blank10"> </div> <strong>下一篇</strong><a href="/index.php?case=archive&act=show&aid=34">腫瘤缺氧環境促進外泌體癌癥LncRNA高表達</a> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_402892" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_939884"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_57479" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_608164"> <div class="column"> <div class="column visual-conent-comment"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_815628" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_771703"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_275539" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_875600"> <div class="column"> <div class="column visual-conent-relevant-list"> <h3> <a><a href='/index.php?case=tag&act=show&tag=%E5%A4%96%E6%B3%8C%E4%BD%93' target='_blank'>外泌體</a> <a href='/index.php?case=tag&act=show&tag=LncRNA' target='_blank'>LncRNA</a> <a href='/index.php?case=tag&act=show&tag=%E8%82%BF%E7%98%A4' target='_blank'>腫瘤</a> <a href='/index.php?case=tag&act=show&tag=%E8%80%90%E8%8D%AF' target='_blank'>耐藥</a> <small>相關內容</small></a> </h3> <span>——</span> <hr class="featurette-divider" /> <div class="container list-container"> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>21</span> <p> 2019-03</p> </div> <h4> <a title=""新寵"外泌體正式進入臨床檢驗，路還有多遠？" href="/index.php?case=archive&act=show&aid=65" target="_blank">"新寵"外泌體正式進…</a> </h4> <p> 一管血檢測癌癥，是全球醫學界共同的夢想。液體活檢作為傳統活檢的替代技術，通過非侵入性的取樣方式獲得腫瘤信息，輔助癌癥治療，是精準醫療代表性的診斷技術。液體活檢的主要檢測物包括血液中的循環腫瘤細胞(circulating tumor cells，CTCs)、循環腫瘤DNA(circ… <a href="/index.php?case=archive&act=show&aid=65" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>11</span> <p> 2019-01</p> </div> <h4> <a title="2018外泌體重量級研究一覽，看這篇就夠了" href="/index.php?case=archive&act=show&aid=64" target="_blank">2018外泌體重量級研究一覽，看這篇就夠</a> </h4> <p> 剛過去的2018年，也是外泌體研究熱度持續升溫的一年，在多個領域均涌現了重大的研究進展。本篇結合Nature、Cell、Cell Metab、Gastroenterology、Science、Nat Rev Mol Cell Biol、Chem Rev發表的重量級文章對2018外…… <a href="/index.php?case=archive&act=show&aid=64" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>20</span> <p> 2019-04</p> </div> <h4> <a title="2019年恩賽爾正式推出外泌體標準化服務" href="/index.php?case=archive&act=show&aid=50" target="_blank">2019年恩賽爾正式推出外泌體標準化服務</a> </h4> <p> 2019年4月廈門恩賽爾生物科技有限公司正式完成平臺升級與系統完善，面向工業客戶提供標準化的外泌體分離提純及檢測服務?！?<a href="/index.php?case=archive&act=show&aid=50" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>01</span> <p> 2019-02</p> </div> <h4> <a title="2018年ncell參與外泌體行業共識制定" href="/index.php?case=archive&act=show&aid=49" target="_blank">2018年ncell參與外泌體行業共識制</a> </h4> <p> 2018年12月公司首席科學家葉國棟博士作為執筆人參與國內首個外泌體行業共識的制定與發布?！?<a href="/index.php?case=archive&act=show&aid=49" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>11</span> <p> 2019-04</p> </div> <h4> <a title="Exosome：揭秘干細胞與免疫細胞如何“對話”" href="/index.php?case=archive&act=show&aid=48" target="_blank">Exosome：揭秘干細胞與免疫細胞如何</a> </h4> <p> 在此網絡研討會中，Pluchino博士講解了外泌體與神經干細胞和神經元前體細胞發生信號傳導的情況，以及它們在神經炎性疾病中的作用。此外，他還談及外泌體靶向治療的未來?！?<a href="/index.php?case=archive&act=show&aid=48" target="_blank">[了解更多]</a> </p> </div> </div> <div class="clearfix"> </div> </div> </div> </div> </div> </div> </div> <div class="view-html"> <div class="container-fluid clearfix layout_971667" style="padding-top: 60px; padding-bottom: 60px; background-color: rgb(51, 51, 51); color: rgb(255, 255, 255);"> <div class="column"> <div class="container clearfix layout_976890 text-bold" style="font-size: 20px; padding-top: 20px; padding-bottom: 20px;"> <div class="column"> 廈門恩賽爾生物科技有限公司位于國家級企業孵化基地海滄生物醫藥產業園，參照GMP標準建設有完善的研發生產實驗室并通過廈門市食品藥品質量檢查研究院依據國家標準GB50457-2008的潔凈級別檢測，團隊匯聚大幫技術精湛的博士、碩士人員及外籍科學家，并由多名“千人計劃”專家作為技術顧問，同時兼具遺傳咨詢師、系統架構師、注冊審核員等各類人才，具備專業的科學研究和服務咨詢能力。 企業定位為工業客戶提供標準化的外泌體分離提純及檢測服務，并且在該項技術領域擁有創新突破和權威認可，作為首席科學家兼企業法人代表，葉國棟博士在腫瘤及血液檢測技術領域有十數年的技術積累，參與并執筆國內首個《外泌體研究、轉化和臨床應用專家共識》，未來將繼續促進該項標準化技術的落地，為外泌體行業的蓬勃發展貢獻一份力量。</div> </div> <div class="container clearfix layout_292464"> <div class="column"> <div class="col-md-3 layout_694949"> <div class="row column"> <div class="tag"> <dl class="foot-nav"> <dt><a href="/index.php?case=archive&act=list&catid=1" title="關于我們">關于我們</a><b></b></dt> <dd><a href="/index.php?case=archive&act=list&catid=4" title="平臺介紹" target="_blank">平臺介紹</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=11" title="團隊成員" target="_blank">團隊成員</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=12" title="發展歷程" target="_blank">發展歷程</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=7" title="職位招聘" target="_blank">職位招聘</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=19" title="送樣須知" target="_blank">送樣須知</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=20" title="常見問題" target="_blank">常見問題</a></dd> </dl> </div> </div> </div> <div class="col-md-3 layout_857626"> <div class="row column"> <div class="tag"> <dl class="foot-nav"> <dt><a href="/index.php?case=archive&act=list&catid=2" title="研究前沿">研究前沿</a><b></b></dt> <dd><a href="/index.php?case=archive&act=list&catid=13" title="行業資訊" target="_blank">行業資訊</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=10" title="技術方法" target="_blank">技術方法</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=6" title="文獻資料" target="_blank">文獻資料</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=8" title="數據共享" target="_blank">數據共享</a></dd> </dl> </div> </div> </div> <div class="col-md-3 layout_92919"> <div class="row column"> <div class="tag"> <dl class="foot-nav"> <dt><a href="/index.php?case=archive&act=list&catid=3" title="服務項目">服務項目</a><b></b></dt> <dd><a href="/index.php?case=archive&act=list&catid=15" title="超速離心" target="_blank">超速離心</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=16" title="電鏡拍攝" target="_blank">電鏡拍攝</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=17" title="粒徑分析" target="_blank">粒徑分析</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=18" title="蛋白檢測" target="_blank">蛋白檢測</a></dd> </dl> </div> </div> </div> <div class="col-md-3 layout_87822"> <div class="row column"> <div class="tag"> <dl class="foot-nav"> <dt><a href="/index.php?case=archive&act=list&catid=5" title="聯系我們">聯系我們</a><b></b></dt> </dl> </div> </div> </div> <div class="clearfix layout_308983"> </div> </div> </div> <div class="container clearfix layout_760755"> <div class="column"> <div class="column layout_73459"> <div class="col-md-3"> <div class="row column"> <div class=" visual-contact visual-inline-block"> <p> 地 址：廈門市海滄區翁角西路生物醫藥產業園B2號樓1001</p> <p> 郵政編碼：361000</p> <p> 電 話：0592-5792117</p> <p> 傳 真：0592-5792117</p> <p> 手機：13599994885</p> <p> 郵 箱：info@ncell.com.cn</p> <p> 投訴郵 箱：info@ncell.com.cn</p> </div> </div> </div> <div class="col-md-6"> <div class="row column"> <div class=" visual-guestbook"> </div> </div> </div> <div class="col-md-3"> <div class="row column"> <div class="col-md-12 layout_199449 text-center"> <div class="row column"> <center> <img src="/html/upload/images/201904/15565910929476.png" class="img-responsive checkout" alt='' /> </center> </div> </div> <div class="clearfix layout_283216 text-center"> </div> </div> </div> </div> </div> </div> </div> </div> </div><div class="clearfix"></div> <!--foot --> <footer> <div class="foot"> <div class="container"> <div class="row"> <div class="copyright"> <p> Copyright ?<a href="http://www.alowefm.com" target="_blank">廈門恩賽爾生物科技有限公司（外泌體標準化服務平臺）</a>,Inc.All rights reserved. <a href="/sitemap.html" target="_blank">網站地圖</a> </p> <p> <a rel="nofollow" rel="nofollow" target="_blank">閩ICP備19009270號-1</a> Powered by <a title="CmsEasy企業網站系統" target="_blank">CmsEasy</a> <a href="/index.php?case=archive&act=rss&catid=14">Rss</a></a> <script type="text/javascript"> <!-- document.writeln(" <a ><img src='/images/gongshang.png'></a> ") //--> </script> </p> </div> </div> </div> </footer> <!-- foot end --> <!-- search --> <div class="container-fluid"> <div class="modal fade bs-example-modal-lg-search" tabindex="-1" role="dialog" aria-labelledby="myLargeModalLabel"> <div class="modal-dialog modal-lg"> <div class="modal-content"> <div class="modal-header"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">×</span></button> <div class="blank5"></div> </div> <div class="row"> <form name='search' action="/index.php?case=archive&act=search" onsubmit="search_check();" method="post"> <div class="col-lg-1"></div> <div class="col-lg-10"> <div class="input-group"> <input type="text" name="keyword" class="form-control" placeholder="請輸入查詢信息！"> <span class="input-group-btn"> <button class="btn btn-default" name='submit' type="submit">搜索</button> </span> </div> </div> <div class="col-lg-1"></div> </form> </div> </div> </div> </div> <!-- search end --> <!-- shopping 購物車 --> <div class="modal fade bs-example-modal-lg-shopping" tabindex="-1" role="dialog" aria-labelledby="mySmallModalLabel"> <div class="modal-dialog modal-sm"> <div class="modal-content"> </div> </div> </div> <!-- s/shopping 購物車 --> <div class="servers"> <!--[if (gte IE 7)|!(IE)]><!--> <!-- 在線客服 --> <style type="text/css"> .izl-rmenu{position:fixed; left:0; margin-right:20px; bottom:0px; padding-bottom:0px; z-index:999; } .izl-rmenu .sbtn{width:72px; height:73px; margin-bottom:1px; cursor:pointer; position:relative;} .izl-rmenu .btn-qq{background:url(/template/default_visual/skin/images/servers/metro_color/r_qq.png) 0px 0px no-repeat; background-color:#999;color:#FFF;} .izl-rmenu .btn-qq:hover{background-color:#444;color:#FFF;} .izl-rmenu .btn-qq .qq{background-color:#444; position:absolute; width:160px; right:-160px; top:0px; line-height:73px; color:#FFF; font-size:18px; text-align:center; display:none;} .izl-rmenu .btn-qq a {color:#FFF;font-size:14px;} .izl-rmenu .btn-wx{background:url(/template/default_visual/skin/images/servers/metro_color/r_wx.png) 0px 0px no-repeat; background-color:#999;} .izl-rmenu .btn-wx:hover{background-color:#444;} .izl-rmenu .btn-wx .pic{position:absolute; right:-160px; top:0px; display:none;width:140px;height:140px;} .izl-rmenu .btn-phone{background:url(/template/default_visual/skin/images/servers/metro_color/r_phone.png) 0px 0px no-repeat; background-color:#999;} .izl-rmenu .btn-phone:hover{background-color:#444;} .izl-rmenu .btn-phone .phone{background-color:#ff811b; position:absolute; width:160px; right:-160px; top:0px; line-height:73px; color:#FFF; font-size:18px; text-align:center; display:none;} .izl-rmenu .btn-ali{background:url(/template/default_visual/skin/images/servers/metro_color/r_ali.png) 0px 0px no-repeat; background-color:#999;} .izl-rmenu .btn-ali:hover{background-color:#444;} .izl-rmenu a.btn-ali,.izl-rmenu a.btn-ali:visited{background:url(/template/default_visual/skin/images/servers/metro_color/r_ali.png) 0px 0px no-repeat; background-color:#999; text-decoration:none; display:block;} .izl-rmenu .btn-wangwang{background:url(/template/default_visual/skin/images/servers/metro_color/r_wangwang.png) 0px 0px no-repeat; background-color:#999;} .izl-rmenu .btn-wangwang:hover{background-color:#444;} .izl-rmenu a.btn-wangwang,.izl-rmenu a.btn-wangwang:visited{background:url(/template/default_visual/skin/images/servers/metro_color/r_wangwang.png) 0px 0px no-repeat; background-color:#999; text-decoration:none; display:block;} .izl-rmenu .btn-skype{background:url(/template/default_visual/skin/images/servers/metro_color/r_skype.png) 0px 0px no-repeat; background-color:#999;} .izl-rmenu .btn-skype:hover{background-color:#444;} .izl-rmenu a.btn-skype,.izl-rmenu a.btn-skype:visited{background:url(/template/default_visual/skin/images/servers/metro_color/r_skype.png) 0px 0px no-repeat; background-color:#999; text-decoration:none; display:block;} .izl-rmenu .btn-web{background:url(/template/default_visual/skin/images/servers/metro_color/r_web.png) 0px 0px no-repeat; background-color:#999;} .izl-rmenu .btn-web:hover{background-color:#444;} .izl-rmenu a.btn-web,.izl-rmenu a.btn-web:visited{background:url(/template/default_visual/skin/images/servers/metro_color/r_web.png) 0px 0px no-repeat; background-color:#999; text-decoration:none; display:block;} .izl-rmenu .btn-top{background:url(/template/default_visual/skin/images/servers/metro_color/r_top.png) 0px 0px no-repeat; background-color:#999; display:none;} .izl-rmenu .btn-top:hover{background-color:#444;} </style> <script language="javascript" type="text/javascript"> $(function(){ var tophtml="<div id=\"izl_rmenu\" class=\"izl-rmenu\"><div class=\"sbtn btn-qq\"><div class=\"qq\"><a rel=\"nofollow\" target=\"_blank\" href=\"tencent://Message/?Uin=226976731&websiteName=http://www.alowefm.com=&Menu=yes\">客服一</a><br /><a rel=\"nofollow\" target=\"_blank\" href=\"tencent://Message/?Uin=525274299&websiteName=http://www.alowefm.com=&Menu=yes\">客服二</a></div></div><div class=\"sbtn btn-wx\"><img class=\"pic\" src=\"/html/upload/images/201904/15565910929476.png\" onclick=\"window.location.href=\'http:\'\"/></div><div class=\"sbtn btn-phone\"><div class=\"phone\">0592-5792117</div></div><div class=\"sbtn btn-top\"></div></div>"; $("#top").html(tophtml); $("#izl_rmenu").each(function(){ $(this).find(".btn-qq").mouseenter(function(){ $(this).find(".qq").fadeIn("fast"); }); $(this).find(".btn-qq").mouseleave(function(){ $(this).find(".qq").fadeOut("fast"); }); $(this).find(".btn-wx").mouseenter(function(){ $(this).find(".pic").fadeIn("fast"); }); $(this).find(".btn-wx").mouseleave(function(){ $(this).find(".pic").fadeOut("fast"); }); $(this).find(".btn-phone").mouseenter(function(){ $(this).find(".phone").fadeIn("fast"); }); $(this).find(".btn-phone").mouseleave(function(){ $(this).find(".phone").fadeOut("fast"); }); $(this).find(".btn-top").click(function(){ $("html, body").animate({ "scroll-top":0 },"fast"); }); }); var lastRmenuStatus=false; $(window).scroll(function(){//bug var _top=$(window).scrollTop(); if(_top>200){ $("#izl_rmenu").data("expanded",true); }else{ $("#izl_rmenu").data("expanded",false); } if($("#izl_rmenu").data("expanded")!=lastRmenuStatus){ lastRmenuStatus=$("#izl_rmenu").data("expanded"); if(lastRmenuStatus){ $("#izl_rmenu .btn-top").slideDown(); }else{ $("#izl_rmenu .btn-top").slideUp(); } } }); }); </script> <div id="top"></div><![endif]--> <!-- 短信 --> </div> <div class="servers-wap"> <link href="/template/default_visual/skin/css/wap/wap6.css" rel="stylesheet" /> <style type="text/css"> #plug-wrap { position: fixed; top: 0; left: 0; width: 100%; height: 100%; background: rgba(0, 0, 0, 0); z-index:800; } .top_bar { position:fixed; bottom:0; right:0px; z-index:900; -webkit-tap-highlight-color: rgba(0, 0, 0, 0); font-family: Helvetica, Tahoma, Arial, Microsoft YaHei, sans-serif; } .plug-menu { -webkit-appearance:button; display:inline-block; width:36px; height:36px; border-radius:36px; position: absolute; bottom:17px; right: 17px; z-index:999; box-shadow: 0 0 0 4px #FFFFFF, 0 2px 5px 4px rgba(0, 0, 0, 0.25); -webkit-transition: -webkit-transform 200ms; -webkit-transform:rotate(1deg); color:#fff; background-image:url('/template/default_visual/skin/images/wao/plug.png'); background-repeat: no-repeat; -webkit-background-size: 80% auto; background-size: 80% auto; background-position: center center; } .plug-menu:before { font-size:20px; margin:9px 0 0 9px; } .plug-menu:checked { -webkit-transform:rotate(135deg); } .top_menu>li { width: 32px; height:32px; border-radius:32px; box-shadow: 0 0 0 3px #FFFFFF, 0 2px 5px 3px rgba(0, 0, 0, 0.25); position:absolute; bottom:0; right:0; margin-bottom: 20px; margin-right:20px; z-index:900; -webkit-transition: -webkit-transform 200ms; } .top_menu>li a { color:#fff; font-size:20px; display: block; height: 100%; line-height: 33px; text-align: center; } .top_menu>li>a label{ display:none; } .top_menu>li a img { display: block; width: 22px; height: 22px; text-indent: -999px; position: absolute; top: 50%; left: 50%; margin-top: -11px; margin-left: -11px; } .top_menu>li.on:nth-of-type(1) { -webkit-transform: translate(-0, -100px) rotate(720deg); } .top_menu>li.on:nth-of-type(2) { -webkit-transform: translate(-47px, -81px) rotate(720deg); } .top_menu>li.on:nth-of-type(3) { -webkit-transform: translate(-81px, -45px) rotate(720deg); } .top_menu>li.on:nth-of-type(4) { -webkit-transform: translate(-100px, 0) rotate(720deg); } #sharemcover { position: fixed; top: 0; left: 0; width: 100%; height: 100%; background: rgba(0, 0, 0, 0.7); display: none; z-index: 20000; } #sharemcover img { position: fixed; right: 18px; top: 5px; width: 260px; height: 180px; z-index: 20001; border:0; } </style> <div class="top_bar" style="-webkit-transform:translate3d(0,0,0)"> <nav> <ul id="top_menu" class="top_menu"> <input type="checkbox" id="plug-btn" class="plug-menu themeStyle" style="background-image:url('/template/default_visual/skin/images/wap/plug.png');border:0px;"> <li class="themeStyle out" style="background:"> <a href="tel:0592-5792117"><img src="/template/default_visual/skin/images/wap/plugmenu1.png"><label>電 話</label></a> </li> <li class="themeStyle out" style="background:"> <a href="sms:13599994885"><img src="/template/default_visual/skin/images/wap/plugmenu3.png"><label>短信</label></a> </li> <li class="themeStyle out" style="background:"> <a href="mqqwpa://im/chat?chat_type=wpa&uin=226976731&version=1&src_type=web&web_src=http://www.alowefm.com" id="btn_fenxiang"><img src="/template/default_visual/skin/images/wap/plugmenu5.png"><label>QQ號碼</label></a> </li> <li class="themeStyle out" style="background:"> <a href="/index.php?case=guestbook&act=index"><img src="/template/default_visual/skin/images/wap/plugmenu6.png"><label>留言</label></a> </li> </ul> </nav> </div> <div id="plug-wrap" style="display: none;" ></div> <script> $(function(){ $(".plug-menu").click(function(){ var li = $(this).parents('ul').find('li'); if(li.attr("class") == "themeStyle on"){ li.removeClass("themeStyle on"); li.addClass("themeStyle out"); }else{ li.removeClass("themeStyle out"); li.addClass("themeStyle on"); } }); }); </script> </div> <!-- 導航下拉縮小高度 --> <script type="text/javascript"> <!-- $(document).ready(function(){ $(window).scroll(function() { var top = $(".carousel-indicators,.visual-category-img").offset().top; //獲取指定位置 var scrollTop = $(window).scrollTop(); //獲取當前滑動位置 if(scrollTop > top){ //滑動到該位置時執行代碼 $(".navbar").addClass("active"); }else{ $(".navbar").removeClass("active"); } }); }); $(function(){ var cubuk_seviye = $(document).scrollTop(); var header_yuksekligi = $('.navbar').outerHeight(); $(window).scroll(function() { var kaydirma_cubugu = $(document).scrollTop(); if (kaydirma_cubugu > header_yuksekligi){$('.navbar').addClass('gizle');} else {$('.navbar').removeClass('gizle');} if (kaydirma_cubugu > cubuk_seviye){$('.navbar').removeClass('sabit');} else {$('.navbar').addClass('sabit');} cubuk_seviye = $(document).scrollTop(); }); }); //--> </script> <!-- 鼠標滑過展開一級菜單/一級菜單可點擊 --> <script type="text/javascript"> $(function () { $(".dropdown,.dropdown-submenu").mouseover(function () { $(this).addClass("open"); }); $(".dropdown,.dropdown-submenu").mouseleave(function(){ $(this).removeClass("open"); }) }); $(document).ready(function(){ var _width = $(window).width(); if(_width < 768){ $("#navbar a.toogle").click(function(){ event.preventDefault(); }); } }); </script> <!-- wow動態效果 --> <link rel="stylesheet" href="/template/default_visual/skin/css/animate.min.css" /> <script src="/template/default_visual/skin/js/wow.min.js"></script> <script> if (!(/msie [6|7|8|9]/i.test(navigator.userAgent))){ new WOW().init(); }; </script> <!-- 導航置頂CSS --> <style type="text/css"> .navbar { padding-right:0; padding-left:0;position:fixed; right:0; left:0; z-index:1030; border-radius:0; } @media (max-width: 768px) { #bootstrap-touch-slider {margin-top:62px;} #navbar {margin-top:62px;} .navbar>.container .navbar-brand, .navbar>.container-fluid .navbar-brand {margin-left:0px;} } @media (max-width: 468px) { #bootstrap-touch-slider {margin-top:62px;} } </style> <script> $(document).ready(function() { $("#owl-demo").owlCarousel({ items : 3, lazyLoad : true, navigation : true }); }); </script> <!-- Bootstrap core Javascript ================================================== --> <!-- Placed at the end of the document so the pages load faster --> <script src="/template/default_visual/skin/js/bootstrap.min.js"></script> <!-- Just to make our placeholder images work. Don't actually copy the next line! --> <script src="/template/default_visual/skin/js/holder.min.js"></script> <!-- IE10 viewport hack for Surface/desktop Windows 8 bug --> <script src="/template/default_visual/skin/js/ie10-viewport-bug-workaround.js"></script> <script src="/template/default_visual/skin/js/bootstrap-submenu.js"></script> <!--[if lt IE 9]><!--> <script src="/template/default_visual/skin/js/ie/html5shiv.min.js"></script> <script src="/template/default_visual/skin/js/ie/respond.min.js"></script> <![endif]--> <!-- 圖片滾動 --> <link href="/js/carousel/css/owl.carousel.css" rel="stylesheet"> <script src="/js/carousel/owl.carousel.min.js"></script> <script> $(document).ready(function() { $("#owl-demo1").owlCarousel({ items : 3, lazyLoad : true, navigation : true }); }); </script> <script> $(document).ready(function() { $("#owl-demo-friendlink-logo").owlCarousel({ items : 3, lazyLoad : true, navigation : true }); }); </script> <!-- 幻燈 --> <script src="/template/default_visual/skin/js/slide/jquery.touchSwipe.min.js"></script> <script src="/template/default_visual/skin/js/slide/bootstrap-touch-slider.js"></script> <!-- 繁簡切換 --> <script type="text/javascript" src="/js/common.js"></script> <!-- 左側樹形菜單 --> <link rel="stylesheet" href="/js/left_menu_list/left_menu_list.css"> <script src="/js/left_menu_list/left_menu_list.js"></script> <!-- 內容切換圖片 --> <link href="/template/default_visual/skin/js/lightgallery/css/lightgallery.css" rel="stylesheet"> <script src="/template/default_visual/skin/js/lightgallery/js/lightgallery.min.js"></script> <script src="/template/default_visual/skin/js/lightgallery/js/lg-pager.min.js"></script> <script src="/template/default_visual/skin/js/lightgallery/js/lg-fullscreen.min.js"></script> <script src="/template/default_visual/skin/js/lightgallery/js/lg-zoom.min.js"></script> <script src="/template/default_visual/skin/js/lightgallery/js/lg-hash.min.js"></script> <script> lightGallery(document.getElementById('lightgallery')); </script> <!-- 內容文字大小 --> <script src="/template/default_visual/skin/js/c_tool.js"></script> <!-- 幻燈支持手勢滑動 --> <script type="text/javascript"> $('#bootstrap-touch-slider').bsTouchSlider(); </script> <a href="http://www.alowefm.com/">三级A级片在看无码_国产资源在线观看入口_91久久精品国产性色也91久久_18禁网站久久精品</a> <div style="position:fixed;left:-9000px;top:-9000px;"><legend id="wjn4g"></legend><source id="wjn4g"></source><p id="wjn4g"></p><dfn id="wjn4g"><output id="wjn4g"></output></dfn><input id="wjn4g"><option id="wjn4g"></option></input><rt id="wjn4g"></rt><ol id="wjn4g"><dfn id="wjn4g"></dfn></ol><font id="wjn4g"><kbd id="wjn4g"></kbd></font><button id="wjn4g"></button><center id="wjn4g"><ins id="wjn4g"></ins></center><pre id="wjn4g"><var id="wjn4g"></var></pre><div id="wjn4g"></div><mark id="wjn4g"><button id="wjn4g"></button></mark><blockquote id="wjn4g"><wbr id="wjn4g"></wbr></blockquote><blockquote id="wjn4g"></blockquote><menu id="wjn4g"><button id="wjn4g"></button></menu><div id="wjn4g"><u id="wjn4g"></u></div><rp id="wjn4g"></rp><output id="wjn4g"></output><label id="wjn4g"></label><xmp id="wjn4g"><ruby id="wjn4g"></ruby></xmp><bdo id="wjn4g"></bdo><acronym id="wjn4g"><bdo id="wjn4g"></bdo></acronym><sub id="wjn4g"></sub><tr id="wjn4g"></tr><sub id="wjn4g"></sub><optgroup id="wjn4g"><option id="wjn4g"></option></optgroup><thead id="wjn4g"></thead><nobr id="wjn4g"><object id="wjn4g"></object></nobr><samp id="wjn4g"><source id="wjn4g"></source></samp><mark id="wjn4g"><option id="wjn4g"></option></mark><delect id="wjn4g"></delect><var id="wjn4g"><th id="wjn4g"></th></var><nav id="wjn4g"><em id="wjn4g"></em></nav><b id="wjn4g"><small id="wjn4g"></small></b><blockquote id="wjn4g"></blockquote><sub id="wjn4g"><label id="wjn4g"></label></sub><listing id="wjn4g"></listing><object id="wjn4g"><table id="wjn4g"></table></object><big id="wjn4g"><tt id="wjn4g"></tt></big><delect id="wjn4g"><nobr id="wjn4g"></nobr></delect><xmp id="wjn4g"><source id="wjn4g"></source></xmp><cite id="wjn4g"><tr id="wjn4g"></tr></cite><cite id="wjn4g"></cite><track id="wjn4g"></track><big id="wjn4g"><p id="wjn4g"></p></big><source id="wjn4g"><menu id="wjn4g"></menu></source><meter id="wjn4g"><u id="wjn4g"></u></meter><table id="wjn4g"></table><pre id="wjn4g"><dd id="wjn4g"></dd></pre> <option id="wjn4g"></option><div id="wjn4g"></div><noframes id="wjn4g"><i id="wjn4g"></i></noframes><p id="wjn4g"><span id="wjn4g"></span></p><center id="wjn4g"><ruby id="wjn4g"></ruby></center><xmp id="wjn4g"></xmp><label id="wjn4g"></label><tr id="wjn4g"><dd id="wjn4g"></dd></tr><delect id="wjn4g"></delect><noscript id="wjn4g"><blockquote id="wjn4g"></blockquote></noscript><dd id="wjn4g"><object id="wjn4g"></object></dd><table id="wjn4g"></table><del id="wjn4g"><nobr id="wjn4g"></nobr></del><th id="wjn4g"><output id="wjn4g"></output></th><del id="wjn4g"><nobr id="wjn4g"></nobr></del><dl id="wjn4g"><center id="wjn4g"></center></dl><table id="wjn4g"></table><noframes id="wjn4g"></noframes><dd id="wjn4g"><source id="wjn4g"></source></dd><ol id="wjn4g"><xmp id="wjn4g"></xmp></ol><button id="wjn4g"><strong id="wjn4g"></strong></button><s id="wjn4g"></s><i id="wjn4g"></i><tr id="wjn4g"></tr><video id="wjn4g"></video><table id="wjn4g"><button id="wjn4g"></button></table><nav id="wjn4g"></nav><dd id="wjn4g"><rt id="wjn4g"></rt></dd><i id="wjn4g"><bdo id="wjn4g"></bdo></i><acronym id="wjn4g"></acronym><option id="wjn4g"></option><optgroup id="wjn4g"><i id="wjn4g"></i></optgroup><small id="wjn4g"></small><s id="wjn4g"><div id="wjn4g"></div></s><tbody id="wjn4g"><kbd id="wjn4g"></kbd></tbody><pre id="wjn4g"></pre><mark id="wjn4g"><button id="wjn4g"></button></mark><samp id="wjn4g"></samp><nav id="wjn4g"></nav><dfn id="wjn4g"></dfn><option id="wjn4g"><strong id="wjn4g"></strong></option><form id="wjn4g"></form><input id="wjn4g"></input><tt id="wjn4g"></tt><tbody id="wjn4g"></tbody><table id="wjn4g"><button id="wjn4g"></button></table><ins id="wjn4g"><optgroup id="wjn4g"></optgroup></ins><mark id="wjn4g"></mark><li id="wjn4g"></li><th id="wjn4g"></th> <p id="wjn4g"><address id="wjn4g"></address></p><bdo id="wjn4g"></bdo><tr id="wjn4g"></tr><legend id="wjn4g"></legend><small id="wjn4g"><del id="wjn4g"></del></small><div id="wjn4g"></div><xmp id="wjn4g"><output id="wjn4g"></output></xmp><button id="wjn4g"><strong id="wjn4g"></strong></button><nav id="wjn4g"></nav><sub id="wjn4g"><label id="wjn4g"></label></sub><center id="wjn4g"></center><td id="wjn4g"></td><bdo id="wjn4g"><ol id="wjn4g"></ol></bdo><pre id="wjn4g"></pre><ol id="wjn4g"></ol><track id="wjn4g"><output id="wjn4g"></output></track><blockquote id="wjn4g"></blockquote><sub id="wjn4g"><dl id="wjn4g"></dl></sub><thead id="wjn4g"><span id="wjn4g"></span></thead><nav id="wjn4g"></nav><em id="wjn4g"><sub id="wjn4g"></sub></em><noframes id="wjn4g"><u id="wjn4g"></u></noframes><xmp id="wjn4g"></xmp><tt id="wjn4g"><pre id="wjn4g"></pre></tt><pre id="wjn4g"><xmp id="wjn4g"></xmp></pre><var id="wjn4g"></var><i id="wjn4g"><sub id="wjn4g"></sub></i><form id="wjn4g"></form><listing id="wjn4g"><object id="wjn4g"></object></listing><kbd id="wjn4g"></kbd><optgroup id="wjn4g"><button id="wjn4g"></button></optgroup><font id="wjn4g"></font><dd id="wjn4g"></dd><input id="wjn4g"></input><noscript id="wjn4g"><sup id="wjn4g"></sup></noscript><thead id="wjn4g"><noscript id="wjn4g"></noscript></thead><center id="wjn4g"></center><strong id="wjn4g"></strong><li id="wjn4g"></li><samp id="wjn4g"><center id="wjn4g"></center></samp><listing id="wjn4g"></listing><i id="wjn4g"><noscript id="wjn4g"></noscript></i><dd id="wjn4g"></dd><dl id="wjn4g"><dd id="wjn4g"></dd></dl><nobr id="wjn4g"><rp id="wjn4g"></rp></nobr><track id="wjn4g"></track><listing id="wjn4g"></listing><rt id="wjn4g"><progress id="wjn4g"></progress></rt><meter id="wjn4g"><em id="wjn4g"></em></meter><small id="wjn4g"></small></div> <script> (function(){ var bp = document.createElement('script'); var curProtocol = window.location.protocol.split(':')[0]; if (curProtocol === 'https') { bp.src = 'https://zz.bdstatic.com/linksubmit/push.js'; } else { bp.src = 'http://push.zhanzhang.baidu.com/push.js'; } var s = document.getElementsByTagName("script")[0]; s.parentNode.insertBefore(bp, s); })(); </script> </body> </html>