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</div> <div class="container-fluid clearfix layout_564394 text-center text-bold" style="font-size: 20px; color: rgb(0, 0, 0); margin-top: 30px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_439253"> <div class="column"> <div class="column visual-conent-title"> <p class="content-title"> 血液外泌體miRNA作為非小細胞癌分子標志物分析</p> <div class="clearfix"> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_610181" style="margin-top: 0px;"> <div class="column"> <div class="container clearfix layout_148235 text-center text-bold" style="font-size: 20px; color: rgb(0, 0, 0);"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_369638 text-center" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_13448"> <div class="column"> <div class="col-md-12 layout_455380"> <div class="col-md-2 column"> </div> <div class="col-md-8 column"> <div class="column visual-conent-author visual-inline-block"> <p class="content-author"> <span>作者：</span>admin</p> </div> <div class="column visual-conent-adddate visual-inline-block" style="padding-left: 15px; padding-right: 15px;"> <p class="content-adddate"> <span>添加時間：</span>2019-04-06 13:29:35</p> </div> <div class="column visual-conent-source visual-inline-block"> <p class="content-source"> <span>來源：</span>云序生物</p> </div> <div class="column visual-category-statistics visual-inline-block" style="padding-left: 15px;"> 瀏覽：<script src="/index.php?case=archive&act=view_js&aid=36"></script></div> </div> <div class="col-md-2 column"> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_617573" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_903271"> <div class="column"> <div class="column visual-category-title"> <div class="content_tools_box"> <p class="content_tools"> <a href="javascript:CallPrint('print');">打印本文</a> <a href="javascript:doZoom(14)">小</a> <a href="javascript:doZoom(18)">中</a> <a href="javascript:doZoom(20)">大</a> </p> <div class="clearfix"> </div> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_43304" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_784828"> <div class="column"> <div class="column visual-conent"> <p><strong>題目</strong>：Evaluation of tumor-derived exosomal miRNA as potential diagnostic biomarkers for early stage non-small-cell lung cancer using next-generationsequencing</p><p><strong>期刊</strong>：Clinical Cancer Reserach</p><p><strong>影響因子</strong>：8.78</p><p><strong>簡介</strong>：本文發現腺癌（AC）和鱗癌（SCC）患者的血漿可分離出腫瘤來源外泌體，其中外泌體miRNA極有希望用于NSCLC早期預測和診斷。文章利用miRNA-seq對46個I期NSCLC患者和42個健康個體的外泌體進行miRNA分析，以鑒定和驗證AC和SCC的特異性表達miRNA。結果表明，miR-181-5P、miR-30a-3p、miR-30e-3p和miR-361-5p為AC特異性的；miR-10b-5p、miR-15b-5p和miR-320b為SCC特異性的。后續繪制ROC曲線預測評估三種組合miRNA疾病相關性。事實證明這些miRNA有極大潛力成為NSCLC早期診斷生物標志物。</p><p style="text-align: center;"><img src="/html/upload/images/201904/15563530553353.png" width="780" height="508"/></p></div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_676599" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_158624"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_667472"> <div class="column"> <div class="container clearfix layout_381979"> <div class="column"> <div class=" visual-conent-form"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_886423" style="margin-top: 15px; margin-bottom: 5px;"> <div class="column"> <div class="container clearfix layout_390441"> <div class="column"> <div class="column visual-conent-page"> <div id="page"> <strong>上一篇</strong><a href="/index.php?case=archive&act=show&aid=35">脂肪來源的干細胞分泌外泌體可減輕脂肪炎癥和肥胖現象</a> <div class="blank10"> </div> <strong>下一篇</strong><a href="/index.php?case=archive&act=show&aid=37">尿液中的外泌體可作為往后液體活檢的分子標志物</a> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_402892" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_939884"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_57479" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_608164"> <div class="column"> <div class="column visual-conent-comment"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_815628" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_771703"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_275539" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_875600"> <div class="column"> <div class="column visual-conent-relevant-list"> <h3> <a><a href='/index.php?case=tag&act=show&tag=%E5%A4%96%E6%B3%8C%E4%BD%93' target='_blank'>外泌體</a> <a href='/index.php?case=tag&act=show&tag=%E8%A1%80%E6%B6%B2' target='_blank'>血液</a> <a href='/index.php?case=tag&act=show&tag=miRNA' target='_blank'>miRNA</a> <small>相關內容</small></a> </h3> <span>——</span> <hr class="featurette-divider" /> <div class="container list-container"> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>21</span> <p> 2019-03</p> </div> <h4> <a title=""新寵"外泌體正式進入臨床檢驗，路還有多遠？" href="/index.php?case=archive&act=show&aid=65" target="_blank">"新寵"外泌體正式進…</a> </h4> <p> 一管血檢測癌癥，是全球醫學界共同的夢想。液體活檢作為傳統活檢的替代技術，通過非侵入性的取樣方式獲得腫瘤信息，輔助癌癥治療，是精準醫療代表性的診斷技術。液體活檢的主要檢測物包括血液中的循環腫瘤細胞(circulating tumor cells，CTCs)、循環腫瘤DNA(circ… <a href="/index.php?case=archive&act=show&aid=65" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>11</span> <p> 2019-01</p> </div> <h4> <a title="2018外泌體重量級研究一覽，看這篇就夠了" href="/index.php?case=archive&act=show&aid=64" target="_blank">2018外泌體重量級研究一覽，看這篇就夠</a> </h4> <p> 剛過去的2018年，也是外泌體研究熱度持續升溫的一年，在多個領域均涌現了重大的研究進展。本篇結合Nature、Cell、Cell Metab、Gastroenterology、Science、Nat Rev Mol Cell Biol、Chem Rev發表的重量級文章對2018外…… <a href="/index.php?case=archive&act=show&aid=64" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>20</span> <p> 2019-04</p> </div> <h4> <a title="2019年恩賽爾正式推出外泌體標準化服務" 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href="/index.php?case=archive&act=show&aid=48" target="_blank">[了解更多]</a> </p> </div> </div> <div class="clearfix"> </div> </div> </div> </div> </div> </div> </div> <div class="view-html"> <div class="container-fluid clearfix layout_971667" style="padding-top: 60px; padding-bottom: 60px; background-color: rgb(51, 51, 51); color: rgb(255, 255, 255);"> <div class="column"> <div class="container clearfix layout_976890 text-bold" style="font-size: 20px; padding-top: 20px; padding-bottom: 20px;"> <div class="column"> 廈門恩賽爾生物科技有限公司位于國家級企業孵化基地海滄生物醫藥產業園，參照GMP標準建設有完善的研發生產實驗室并通過廈門市食品藥品質量檢查研究院依據國家標準GB50457-2008的潔凈級別檢測，團隊匯聚大幫技術精湛的博士、碩士人員及外籍科學家，并由多名“千人計劃”專家作為技術顧問，同時兼具遺傳咨詢師、系統架構師、注冊審核員等各類人才，具備專業的科學研究和服務咨詢能力。 企業定位為工業客戶提供標準化的外泌體分離提純及檢測服務，并且在該項技術領域擁有創新突破和權威認可，作為首席科學家兼企業法人代表，葉國棟博士在腫瘤及血液檢測技術領域有十數年的技術積累，參與并執筆國內首個《外泌體研究、轉化和臨床應用專家共識》，未來將繼續促進該項標準化技術的落地，為外泌體行業的蓬勃發展貢獻一份力量。</div> </div> <div class="container clearfix layout_292464"> <div class="column"> <div class="col-md-3 layout_694949"> <div class="row 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