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class="col-md-8 column"> <div class="column visual-conent-author visual-inline-block"> <p class="content-author"> <span>作者：</span>admin</p> </div> <div class="column visual-conent-adddate visual-inline-block" style="padding-left: 15px; padding-right: 15px;"> <p class="content-adddate"> <span>添加時間：</span>2019-04-20 13:12:58</p> </div> <div class="column visual-conent-source visual-inline-block"> <p class="content-source"> <span>來源：</span>永諾生物</p> </div> <div class="column visual-category-statistics visual-inline-block" style="padding-left: 15px;"> 瀏覽：<script src="/index.php?case=archive&act=view_js&aid=42"></script></div> </div> <div class="col-md-2 column"> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_617573" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_903271"> <div class="column"> <div class="column visual-category-title"> <div class="content_tools_box"> <p class="content_tools"> <a href="javascript:CallPrint('print');">打印本文</a> <a href="javascript:doZoom(14)">小</a> <a href="javascript:doZoom(18)">中</a> <a href="javascript:doZoom(20)">大</a> </p> <div class="clearfix"> </div> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_43304" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_784828"> <div class="column"> <div class="column visual-conent"> <p><strong>題目</strong>：Exosome Classification by Pattern Analysis of Surface-enhanced Raman Spectroscopy Data for Lung Cancer Diagnosis</p><p><strong>期刊</strong>：Analytical Chemistry</p><p><strong>影響因子</strong>：5.886</p><p><strong>簡介</strong>：由于外泌體作為細胞間通訊的介質，特別是在癌癥轉移中，證據一直被積累，外泌體可以用作癌癥的非侵入性指標。因此，已有幾項應用外泌體的研究，用于開發癌癥診斷方法，如ELISA測定。然而，由于需要標記過程和高濃度的外泌體，獲得可靠的結果仍然具有挑戰性。本研究中，通過組合表面增強拉曼散射（SERS）和統計模式分析來研究外泌體的無標簽和高敏感的分類方法。</p><p>不同于傳統方法讀取不同的峰位置和頻譜幅度，通過主成分分析（PCA）對外泌體的整個SERS光譜進行分析。通過這種模式分析，將肺癌細胞衍生的外泌體明顯區別于正常細胞衍生的外泌體，靈敏度為95.3％，特異性為97.3％。此外，通過分析PCA結果，研究人員認為這種差異是由來自肺癌細胞衍生的外泌體的SERS信號中的11個不同點引起的。這一結果為外泌體作為癌癥標志物對肺癌進行實時診斷和分類鋪平了道路。</p><p style="text-align: center;"><img src="/html/upload/images/201904/15563551049844.png" width="695" height="412"/></p></div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_676599" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_158624"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_667472"> <div class="column"> <div class="container clearfix layout_381979"> <div class="column"> <div class=" 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</div> <div class="container-fluid clearfix layout_815628" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_771703"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_275539" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_875600"> <div class="column"> <div class="column visual-conent-relevant-list"> <h3> <a><a href='/index.php?case=tag&act=show&tag=%E5%A4%96%E6%B3%8C%E4%BD%93' target='_blank'>外泌體</a> <a href='/index.php?case=tag&act=show&tag=%E8%82%BA%E7%99%8C' target='_blank'>肺癌</a> <a href='/index.php?case=tag&act=show&tag=%E6%8B%89%E6%9B%BC%E5%85%89%E8%B0%B1' target='_blank'>拉曼光譜</a> <small>相關內容</small></a> </h3> <span>——</span> <hr class="featurette-divider" /> <div class="container list-container"> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>21</span> <p> 2019-03</p> </div> <h4> <a title=""新寵"外泌體正式進入臨床檢驗，路還有多遠？" href="/index.php?case=archive&act=show&aid=65" target="_blank">"新寵"外泌體正式進…</a> </h4> <p> 一管血檢測癌癥，是全球醫學界共同的夢想。液體活檢作為傳統活檢的替代技術，通過非侵入性的取樣方式獲得腫瘤信息，輔助癌癥治療，是精準醫療代表性的診斷技術。液體活檢的主要檢測物包括血液中的循環腫瘤細胞(circulating tumor cells，CTCs)、循環腫瘤DNA(circ… <a href="/index.php?case=archive&act=show&aid=65" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>11</span> <p> 2019-01</p> </div> <h4> <a title="2018外泌體重量級研究一覽，看這篇就夠了" href="/index.php?case=archive&act=show&aid=64" target="_blank">2018外泌體重量級研究一覽，看這篇就夠</a> </h4> <p> 剛過去的2018年，也是外泌體研究熱度持續升溫的一年，在多個領域均涌現了重大的研究進展。本篇結合Nature、Cell、Cell Metab、Gastroenterology、Science、Nat Rev Mol Cell Biol、Chem Rev發表的重量級文章對2018外…… <a href="/index.php?case=archive&act=show&aid=64" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>20</span> <p> 2019-04</p> </div> <h4> <a title="2019年恩賽爾正式推出外泌體標準化服務" href="/index.php?case=archive&act=show&aid=50" target="_blank">2019年恩賽爾正式推出外泌體標準化服務</a> </h4> <p> 2019年4月廈門恩賽爾生物科技有限公司正式完成平臺升級與系統完善，面向工業客戶提供標準化的外泌體分離提純及檢測服務?！?<a href="/index.php?case=archive&act=show&aid=50" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>01</span> <p> 2019-02</p> </div> <h4> <a title="2018年ncell參與外泌體行業共識制定" href="/index.php?case=archive&act=show&aid=49" target="_blank">2018年ncell參與外泌體行業共識制</a> </h4> <p> 2018年12月公司首席科學家葉國棟博士作為執筆人參與國內首個外泌體行業共識的制定與發布?！?<a href="/index.php?case=archive&act=show&aid=49" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>11</span> <p> 2019-04</p> </div> <h4> <a title="Exosome：揭秘干細胞與免疫細胞如何“對話”" href="/index.php?case=archive&act=show&aid=48" target="_blank">Exosome：揭秘干細胞與免疫細胞如何</a> </h4> <p> 在此網絡研討會中，Pluchino博士講解了外泌體與神經干細胞和神經元前體細胞發生信號傳導的情況，以及它們在神經炎性疾病中的作用。此外，他還談及外泌體靶向治療的未來?！?<a href="/index.php?case=archive&act=show&aid=48" target="_blank">[了解更多]</a> </p> </div> </div> <div class="clearfix"> </div> </div> </div> </div> </div> </div> </div> <div class="view-html"> <div class="container-fluid clearfix layout_971667" style="padding-top: 60px; padding-bottom: 60px; background-color: rgb(51, 51, 51); color: rgb(255, 255, 255);"> <div class="column"> <div class="container clearfix layout_976890 text-bold" style="font-size: 20px; padding-top: 20px; padding-bottom: 20px;"> <div class="column"> 廈門恩賽爾生物科技有限公司位于國家級企業孵化基地海滄生物醫藥產業園，參照GMP標準建設有完善的研發生產實驗室并通過廈門市食品藥品質量檢查研究院依據國家標準GB50457-2008的潔凈級別檢測，團隊匯聚大幫技術精湛的博士、碩士人員及外籍科學家，并由多名“千人計劃”專家作為技術顧問，同時兼具遺傳咨詢師、系統架構師、注冊審核員等各類人才，具備專業的科學研究和服務咨詢能力。 企業定位為工業客戶提供標準化的外泌體分離提純及檢測服務，并且在該項技術領域擁有創新突破和權威認可，作為首席科學家兼企業法人代表，葉國棟博士在腫瘤及血液檢測技術領域有十數年的技術積累，參與并執筆國內首個《外泌體研究、轉化和臨床應用專家共識》，未來將繼續促進該項標準化技術的落地，為外泌體行業的蓬勃發展貢獻一份力量。</div> </div> <div class="container clearfix 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